Tuesday, August 4, 2020

Rosalind Franklin and Kent State

Rosalind Franklin and Kent State I warn you: this is a depressing entry. Last week I finally finished reading Rosalind Franklin: the Dark Lady of DNA by Brenda Maddox. I say finally because Im pretty sure I actually bought the book at the MIT Press Bookstore the first time I ever visited the campus back in my junior year of high school. Anyway, the biography was great and from what I understand its considered the definitive biography of Franklins life. Everyone knows the basic story of Rosalind Franklin- she took the X-ray photographs that flipped Watsons lightbulb switch regarding the structure of DNA and then proceeded to get no credit for the whole thing because [fill in conspiracy theory here, usually related to her gender]. History hasnt been kind to Rosalind. Im ashamed to say that I didnt even realize how good of a scientist she was until I read the book. Hell, I didnt even realize she was a scientist. I never really thought about it much, but Id somehow always had the impression that she was some kind of X-ray tech, when the truth was that she was considered a world authority on lots of subjects I recognized from 3.091 and developed her own preparation technique that allowed her to take the clearest X-ray photographs anyone had ever seen. The biography is comprehensive, but of course the most interesting passages are those in which Maddox carefully reconstructs the frenzied weeks during which the mysteries of DNA were unravelled. Watson and Crick got access to Rosalinds data and photographs in slightly sketchy ways- not truly and steadfastly unethical but not completely legit either. When they finally cracked the puzzle, they were left in a bit of a mess- they were dying to publish their findings quickly to get the credit for the discovery, but they werent easily able to explain how they figured it out, because they couldnt refer to Rosalinds unpublished data without raising some questions. So they threw in a generic thank you to the people at Kings College, even though most of the people at Kings didnt even know that anyone outside their research group had access to their data. Watson and Crick found her to be a rather disagreeable person, which Watson emphasised in his book, The Double Helix. While Maddox admits that Franklin was sometimes harsh and sarcastic (and I have to say this allowed yours truly to indentify with her more and to find it hard to fault her that without being a rather large hypocrite), she argues that Rosalinds time at Kings was miserable, because no one there respected her. In fact, Rosalind caught on to one important fact before anyone else, but was ignored- in 1951, she claimed that the phosphates of the DNA chains should be located on the outside. Over a year later, after Watson and Crick had seen her photographs and determined that the structure was a helix, they were still struggling to get the whole thing to fit together just right. All of their early models had the phosphates lined up on the inside, which didnt quite work. Later, they tried the other way around, mostly just for the hell of it. Theyd completely missed the eviden ce that she had gathered which actually proved that the phosphates where on the outside. If theyd just collaborated with Rosalind legitimately The Double Helix is famous for portraying Franklin in a poor light (and also being rather sexist with such lines as the best home for a feminist was in another persons lab). Interestingly enough, it seems as if everyone hated the novel. The book was originally going to be published by the Harvard University Press, but virtually every single person who is mentioned complained so loudly about the way the were portrayed that the Harvard Board of Overseers forced Watson to take his book elsewhere. According to Maurice Wilkins (the much less famous third guy who shared the Nobel with Watson and Crick), the book was unfair to me, Dr. Crick and to almost everyone else mentioned except Professor Watson himself. All in all, a pretty good book. I found the beginning a little dry- a little overboard on mundane details of Rosalinds early life. But once you get into the science part of it, some really interesting stuff emerges. After that, I moved on to my next book. Because reading is my sole activity these days. I read The Kent State Coverup, an account of the trials brought against the Ohio National Guard from the point of view of the chief trail counsel for the plaintiffs. Id already read books on the Kent State Shootings themselves. Basically, after a series of riots that trashed downtown Kent, Ohio, the governor sent in the National Guard to keep the peace on the Kent State Campus. On May 4, 1970, the Guard ordered an outdoor rally (protesting their own presence, nonetheless) to disperse. When the students didnt follow the order, the Guardsmen opened fire on the students, wounding 9 and killing 4. Just think about that for a second. A bunch of National Guardsmen, armed with M1 Garand rifles, indiscriminately firing at a bunch of unarmed students for a total of 13 seconds. During the trial, the defense claimed that the students were trying to overtake the Guard, rushing at them, yelling things like kil l the pigs! Nevermind that 2 of the 4 killed werent even attending the rally, but simply walking from one class to the next, or the fact that 8 of the victims were over 300 feet away when they were shot. Am I getting too political here? Sorry, its hard not to. After the shootings, the survivors and parents had to deal with threatening and hateful mail and phone calls, because the average American thought that the students deserved what they got for being anti-establishment hippie Communists. Then they dragged themselves through this trial, where the judge did such absurd things as allow questioning as to the plaintiffs political beliefs, which is complete nonsense that would totally not fly in most courtrooms. The defendents were all universally cleared, leading the mother of one of the dead students to say that the verdict gives license to the government to shoot anyone who doesnt agree with them. After an appeal was granted, the plaintiffs accepted a really lousy settlement instead of going through with the whole trial nonsense again. As if that werent enough, the author of the book is basically a complete jerk (from New York, no surprise there) who thinks hes Gods gift to trial law and is so densely biased himself that he felt challenged to do [his] best in this hostile mid-American atmosphere. In other words, he made a bunch of the other lawyers on his team hate him by taking charge because he wanted to see what it was like try to persuade all the rednecks on the jury. In other news, I smashed my foot on the bottom of my grandparents pool at a family barbeque today, and now it hurts to walk. I told you this was a depressing entry.

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